ERK-TSC2 signalling in constitutively-active HRAS mutant HNSCC cells promotes resistance to PI3K inhibition KM Ruicci, N Pinto, MI Khan, J Yoo, K Fung, D MacNeil, JS Mymryk, ... Oral Oncology 84, 95-103, 2018 | 41 | 2018 |
Repurposing Albendazole: new potential as a chemotherapeutic agent with preferential activity against HPV-negative head and neck squamous cell cancer F Ghasemi, M Black, F Vizeacoumar, N Pinto, KM Ruicci, CCSH Le, ... Oncotarget 8 (42), 71512, 2017 | 39 | 2017 |
Disruption of the RICTOR/mTORC2 complex enhances the response of head and neck squamous cell carcinoma cells to PI3K inhibition KM Ruicci, P Plantinga, N Pinto, MI Khan, W Stecho, SS Dhaliwal, J Yoo, ... Molecular Oncology, 2019 | 31 | 2019 |
Mutational analysis of head and neck squamous cell carcinoma stratified by smoking status F Ghasemi, SD Prokopec, D MacNeil, N Mundi, SF Gameiro, C Howlett, ... JCI insight 4 (1), e123443, 2019 | 31 | 2019 |
A controlled trial of HNSCC patient‐derived xenografts reveals broad efficacy of PI3Kα inhibition in controlling tumor growth KM Ruicci, J Meens, RX Sun, G Rizzo, N Pinto, J Yoo, K Fung, D MacNeil, ... International journal of cancer 145 (8), 2100-2106, 2019 | 30 | 2019 |
Lestaurtinib is a potent inhibitor of anaplastic thyroid cancer cell line models N Pinto, SD Prokopec, F Vizeacoumar, K Searle, M Lowerison, KM Ruicci, ... PloS one 13 (11), e0207152, 2018 | 22 | 2018 |
The genomic and evolutionary landscapes of anaplastic thyroid carcinoma PYF Zeng, SD Prokopec, SY Lai, N Pinto, MA Chan-Seng-Yue, ... Cell Reports 43 (3), 2024 | 19 | 2024 |
Flavopiridol causes cell cycle inhibition and demonstrates anti-cancer activity in anaplastic thyroid cancer models N Pinto, SD Prokopec, F Ghasemi, J Meens, KM Ruicci, IM Khan, N Mundi, ... PloS one 15 (9), e0239315, 2020 | 19 | 2020 |
TAM family receptors in conjunction with MAPK signalling are involved in acquired resistance to PI3Kα inhibition in head and neck squamous cell carcinoma KM Ruicci, J Meens, P Plantinga, W Stecho, N Pinto, J Yoo, K Fung, ... Journal of Experimental & Clinical Cancer Research 39, 1-18, 2020 | 16 | 2020 |
Genomic and human papillomavirus profiling of an oral cancer cohort identifies TP53 as a predictor of overall survival N Mundi, SD Prokopec, F Ghasemi, A Warner, K Patel, D MacNeil, ... Cancers of the head & neck 4, 1-8, 2019 | 16 | 2019 |
High-throughput testing in head and neck squamous cell carcinoma identifies agents with preferential activity in human papillomavirus-positive or negative cell lines F Ghasemi, M Black, RX Sun, F Vizeacoumar, N Pinto, KM Ruicci, J Yoo, ... Oncotarget 9 (40), 26064, 2018 | 15 | 2018 |
Introduction and expression of PIK3CAE545K in a papillary thyroid cancer BRAFV600E cell line leads to a dedifferentiated aggressive phenotype N Pinto, KM Ruicci, MI Khan, MH Shaikh, YFP Zeng, J Yoo, K Fung, ... Journal of Otolaryngology-Head & Neck Surgery 51 (1), 7, 2022 | 13 | 2022 |
Spleen tyrosine kinase expression is correlated with human papillomavirus in head and neck cancer M Black, F Ghasemi, RX Sun, W Stecho, A Datti, J Meens, N Pinto, ... Oral Oncology 101, 104529, 2020 | 10 | 2020 |
Erratum to: Disruption of the RICTOR/mTORC2 complex enhances the response of head and neck squamous cell carcinoma cells to PI3K inhibition KM Ruicci, P Plantinga, N Pinto, MI Khan, W Stecho, SS Dhaliwal, J Yoo, ... Molecular Oncology 14 (1), 230, 2019 | 2 | 2019 |
Aesthetic reconstruction of the Gauge Earlobe: surgical technique and case series KM Ruicci, CC Moore Facial Plastic Surgery & Aesthetic Medicine 24 (4), 332-333, 2022 | 1 | 2022 |
JAK2 as a novel therapeutic target in anaplastic thyroid cancer NC Pinto, K Ruicci, S Prokopec, K Searle, M Lowerison, J Yoo, K Fung, ... Cancer Research 77 (13_Supplement), 2137-2137, 2017 | 1 | 2017 |
The genomic and evolutionary landscapes of anaplastic thyroid carcinoma PYF Zeng, SD Prokopec, SY Lai, N Pinto, MA Chan-Seng-Yue, ... medRxiv, 2023.04. 10.23288365, 2023 | | 2023 |
Mucosal melanoma of the oral cavity KM Ruicci, M Wunder University of Western Ontario Medical Journal 89 (1), 2021 | | 2021 |
Abstract IA02: Utilizing patient-derived xenografts for prognostication and biomarker discovery C Karamboulas, JP Bruce, KM Ruicci, W Xu, AC Nichols, L Ailles Clinical Cancer Research 26 (12_Supplement_2), IA02-IA02, 2020 | | 2020 |
Utilizing patient-derived xenografts for prognostication and biomarker discovery C Karamboulas, JP Bruce, KM Ruicci, W Xu, AC Nichols, L Ailles CLINICAL CANCER RESEARCH 26 (12), 15-15, 2020 | | 2020 |