HIV-1 Nef sequesters MHC-I intracellularly by targeting early stages of endocytosis and recycling BS Dirk, EN Pawlak, AL Johnson, LR Van Nynatten, RA Jacob, B Heit, ... Scientific reports 6 (1), 37021, 2016 | 88 | 2016 |
MIiSR: molecular interactions in super-resolution imaging enables the analysis of protein interactions, dynamics and formation of multi-protein structures FA Caetano, BS Dirk, JHK Tam, PC Cavanagh, M Goiko, SSG Ferguson, ... PLoS computational biology 11 (12), e1004634, 2015 | 48 | 2015 |
The HIV-1 accessory proteins Nef and Vpu downregulate total and cell surface CD28 in CD4+ T cells EN Pawlak, BS Dirk, RA Jacob, AL Johnson, JD Dikeakos Retrovirology 15, 1-22, 2018 | 37 | 2018 |
The interaction between HIV-1 Nef and adaptor protein-2 reduces Nef-mediated CD4+ T cell apoptosis RA Jacob, AL Johnson, EN Pawlak, BS Dirk, LR Van Nynatten, ... Virology 509, 1-10, 2017 | 24 | 2017 |
Antagonistic coevolution of MER tyrosine kinase expression and function AL Evans, JWD Blackburn, K Taruc, A Kipp, BS Dirk, NR Hunt, SD Barr, ... Molecular biology and evolution 34 (7), 1613-1628, 2017 | 22 | 2017 |
Functional and structural mimicry of cellular protein kinase A anchoring proteins by a viral oncoprotein CR King, MJ Cohen, GJ Fonseca, BS Dirk, JD Dikeakos, JS Mymryk PLoS pathogens 12 (5), e1005621, 2016 | 21 | 2016 |
Viral bimolecular fluorescence complementation: a novel tool to study intracellular vesicular trafficking pathways BS Dirk, RA Jacob, AL Johnson, EN Pawlak, PC Cavanagh, ... PLoS One 10 (4), e0125619, 2015 | 19 | 2015 |
Upregulation of BST-2 by type I interferons reduces the capacity of Vpu to protect HIV-1-infected cells from NK cell responses J Prévost, S Pickering, MJ Mumby, H Medjahed, G Gendron-Lepage, ... MBio 10 (3), 10.1128/mbio. 01113-19, 2019 | 16 | 2019 |
A highly conserved residue in HIV-1 Nef alpha helix 2 modulates protein expression AL Johnson, BS Dirk, M Coutu, SMM Haeryfar, EJ Arts, A Finzi, ... MSphere 1 (6), 10.1128/msphere. 00288-16, 2016 | 13 | 2016 |
Where in the cell are you? Probing HIV-1 host interactions through advanced imaging techniques BS Dirk, LR Van Nynatten, JD Dikeakos Viruses 8 (10), 288, 2016 | 13 | 2016 |
DPX-Survivac, a novel T-cell immunotherapy, to induce robust T-cell responses in advanced ovarian cancer. O Dorigo, S Fiset, LD MacDonald, Y Bramhecha, O Hrytsenko, B Dirk, ... Journal of Clinical Oncology 38 (5_suppl), 6-6, 2020 | 11 | 2020 |
Visualizing interactions between HIV-1 nef and host cellular proteins using ground-state depletion microscopy BS Dirk, B Heit, JD Dikeakos AIDS research and human retroviruses 31 (7), 671, 2015 | 11 | 2015 |
PACS-1 and adaptor protein-1 mediate ACTH trafficking to the regulated secretory pathway BS Dirk, C End, EN Pawlak, LR Van Nynatten, RA Jacob, B Heit, ... Biochemical and Biophysical Research Communications 507 (1-4), 519-525, 2018 | 5 | 2018 |
Pathogenic infection of Rhesus macaques by an evolving SIV-HIV derived from CCR5-using envelope genes of acute HIV-1 infections M Asmal, S Lane, M Tian, G Nickel, C Venner, B Dirk, J Dikeakos, ... Virology 499, 298-312, 2016 | 4 | 2016 |
1334 AVA-ADR-001 supresses tumor growth and induces anti-tumor immunity by selectively inhibiting ADAR1 p150 AB Papaiah, A Goswami, S Goyal, K Singh, P Khurana, A Kulkarni Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022 | 1 | 2022 |
Identification of Novel Subcellular Localization and Trafficking of HIV-1 Nef Variants from Reference Strains G (F1. 93. HH8793) and H (BE. 93. VI997) LR Van Nynatten, AL Johnson, BS Dirk, EN Pawlak, RA Jacob, ... Viruses 10 (9), 493, 2018 | 1 | 2018 |
Acetylenic tricyclic bis-(cyano enone) interacts with Cys 374 of actin, a residue necessary for stress fiber formation and cell migration E Chan, BS Dirk, T Honda, PB Stathopulos, JD Dikeakos, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1871 (2), 119629, 2024 | | 2024 |
NK cells are involved in promoting anti-tumor responses to DPX-peptide immunotherapy M Bydoun, D Medina-Luna, B Dirk, J Graff, O Hrytsenko, A Makrigiannis Cancer Research 82 (12_Supplement), 623-623, 2022 | | 2022 |
Proteomic analysis of plasma exosomes as biomarkers of response to MVP-S based immunotherapy P Smith, E Teh, K Chisholm, S Penny, D Pinto, K Patterson, B Dirk, ... The Journal of Immunology 208 (Supplement_1), 66.09-66.09, 2022 | | 2022 |
Abstract LBA026: Survivin peptides formulated in the DPX delivery platform rather than standard emulsions, elicit a robust, sustained T cell response to survivin in advanced … Y Bramhecha, O Dorigo, V Kaliaperumal, H Torrey, W Ebrahimizadeh, ... Molecular Cancer Therapeutics 20 (12_Supplement), LBA026-LBA026, 2021 | | 2021 |