Novel betulin derivatives as antileishmanial agents with mode of action targeting type IB DNA topoisomerase S Chowdhury, T Mukherjee, S Sengupta, SR Chowdhury, ... Molecular pharmacology 80 (4), 694-703, 2011 | 78 | 2011 |
A Novel Spirooxindole Derivative Inhibits the Growth of Leishmania donovani Parasites both In Vitro and In Vivo by Targeting Type IB Topoisomerase S Saha, C Acharya, U Pal, SR Chowdhury, K Sarkar, NC Maiti, ... Antimicrobial Agents and Chemotherapy 60 (10), 6281-6293, 2016 | 61 | 2016 |
Disuccinyl betulin triggers metacaspase-dependent endonuclease G-mediated cell death in unicellular protozoan parasite Leishmania donovani S Chowdhury, T Mukherjee, SR Chowdhury, S Sengupta, ... Antimicrobial agents and chemotherapy 58 (4), 2186-2201, 2014 | 46 | 2014 |
A new bisbenzylisoquinoline alkaloid isolated from Thalictrum foliolosum, as a potent inhibitor of DNA topoisomerase IB of Leishmania donovani A Kumar, SR Chowdhury, T Sarkar, T Chakrabarti, HK Majumder, T Jha, ... Fitoterapia 109, 25-30, 2016 | 42 | 2016 |
Voacamine alters Leishmania ultrastructure and kills parasite by poisoning unusual bi-subunit topoisomerase IB SR Chowdhury, A Kumar, JLP Godinho, STDM Silva, AA Zuma, S Saha, ... Biochemical pharmacology 138, 19-30, 2017 | 39 | 2017 |
The lignan glycosides lyoniside and saracoside poison the unusual type IB topoisomerase of Leishmania donovani and kill the parasite both in vitro and in vivo S Saha, T Mukherjee, S Chowdhury, A Mishra, SR Chowdhury, ... Biochemical Pharmacology 86 (12), 1673-1687, 2013 | 36 | 2013 |
Anthocephaline, a new indole alkaloid and cadambine, a potent inhibitor of DNA topoisomerase IB of Leishmania donovani (LdTOP1LS), isolated from Anthocephalus cadamba A Kumar, SR Chowdhury, KK Jatte, T Chakrabarti, HK Majumder, T Jha, ... Natural Product Communications 10 (2), 1934578X1501000221, 2015 | 35 | 2015 |
Synthesis and biological evaluation of calothrixins B and their deoxygenated analogs BM Ramalingam, ND Moorthy, SR Chowdhury, T Mageshwaran, ... J. Med. Chem 61, 1285-1315, 2018 | 27 | 2018 |
DNA Topoisomerases in unicellular pathogens: structure, function, and druggability SR Chowdhury, HK Majumder Trends in biochemical sciences 44 (5), 415-432, 2019 | 24 | 2019 |
Isobenzofuranone derivatives exhibit antileishmanial effect by inhibiting type II DNA topoisomerase and inducing host response A Mishra, J Vinayagam, S Saha, S Chowdhury, S Roychowdhury, ... Pharmacology Research & Perspectives 2 (6), e00070, 2014 | 22 | 2014 |
A New Ellagic Acid Glycoside and DNA Topoisomerase IB Inhibitory Activity of Saponins from Putranjiva roxburghii A Kumar, SR Chowdhury, T Chakrabarti, HK Majumdar, T Jha, ... Natural Product Communications 9 (5), 1934578X1400900523, 2014 | 20 | 2014 |
Isobenzofuranone derivative JVPH3, an inhibitor of L. donovani topoisomerase II, disrupts mitochondrial architecture in trypanosomatid parasites SR Chowdhury, JLP Godinho, J Vinayagam, AA Zuma, STDM Silva, ... Scientific Reports 8 (1), 11940, 2018 | 17 | 2018 |
Synthesis and biological evaluation of calothrixins B and their deoxygenated analogues B Muthu Ramalingam, N Dhatchana Moorthy, SR Chowdhury, ... Journal of Medicinal Chemistry 61 (3), 1285-1315, 2018 | 13 | 2018 |
DNA topoisomerases of kinetoplastid parasites: brief overview and recent perspectives S Saha, SR Chowdhury, HK Majumder Current Issues in Molecular Biology 31 (1), 45-62, 2019 | 10 | 2019 |
Divergent Synthesis and Evaluation of the in vitro Cytotoxicity Profiles of 3, 4‐Ethylenedioxythiophenyl‐2‐propen‐1‐one Analogues J Karunakaran, N Dhatchana Moorthy, SR Chowdhury, S Iqbal, ... ChemMedChem 14 (15), 1418-1430, 2019 | 7 | 2019 |
TDP1 knockout Leishmania donovani accumulate topoisomerase 1‐linked DNA damage and are hypersensitive to clinically used antileishmanial drugs SR Chowdhury, SK Das, B Banerjee, S Paul Chowdhuri, HK Majumder, ... The FASEB Journal 36 (4), e22265, 2022 | 5 | 2022 |
Targeting DNA topoisomerases in parasitic protozoa by natural products: Chemical and biological perspectives SR Chowdhury, VK Gupta, HK Majumder Studies in Natural Products Chemistry 67, 389-410, 2020 | 4 | 2020 |
Type II DNA topoisomerases in trypanosomatid and apicomplexan parasites SR Chowdhury, A Bhoumik, VK Gupta, HK Majumder Acta Tropica 234, 106613, 2022 | 1 | 2022 |
Targeting topoisomerases for antileishmanial chemotherapeutics and deciphering the role of Mre11 in topoisomerase induced DNA damage repair in Leishmania donovani SR Chowdhury, HK Majumder FASEB JOURNAL_SUPPLEMENT 32 (1), 2018 | | 2018 |