| The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bɛ at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen … YL WOODS, P COHEN, W BECKER, R JAKES, M GOEDERT, W Xuemin, ... Biochemical Journal 355 (3), 609-615, 2001 | 400 | 2001 |
| Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases W Becker, Y Weber, K Wetzel, K Eirmbter, FJ Tejedor, HG Joost Journal of Biological Chemistry 273 (40), 25893-25902, 1998 | 346 | 1998 |
| The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site YL WOODS, R Graham, N MORRICE, A BARTHEL, W BECKER, ... Biochemical Journal 355 (3), 597-607, 2001 | 331 | 2001 |
| Dyrk, a dual specificity protein kinase with unique structural features whose activity is dependent on tyrosine residues between subdomains VII and VIII H Kentrup, W Becker, J Heukelbach, A Wilmes, A Schürmann, C Huppertz, ... Journal of Biological Chemistry 271 (7), 3488-3495, 1996 | 317 | 1996 |
| Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation N Göckler, G Jofre, C Papadopoulos, U Soppa, FJ Tejedor, W Becker FEBS Journal 276 (21), 6324-6337, 2009 | 304 | 2009 |
| Structural and functional characteristics of Dyrk, a novel subfamily of protein kinases with dual specificity W Becker, HG Joost Progress in nucleic acid research and molecular biology 62, 1-17, 1998 | 297 | 1998 |
| Specificity determinants of substrate recognition by the protein kinase DYRK1A S Himpel, W Tegge, R Frank, S Leder, HG Joost, W Becker Journal of Biological Chemistry 275 (4), 2431-2438, 2000 | 287 | 2000 |
| Activation, regulation, and inhibition of DYRK1A W Becker, W Sippl FEBS Journal 278 (2), 246-256, 2011 | 259 | 2011 |
| Differences in gene expression between natural and artificially induced leaf senescence W Becker, K Apel Planta 189 (1), 74-79, 1993 | 245 | 1993 |
| Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A S HIMPEL, P PANZER, K EIRMBTER, H CZAJKOWSKA, M SAYED, ... Biochem. J 359, 497-505, 2001 | 239 | 2001 |
| The identification of leaf thionin as one of the main jasmonate-induced proteins of barley (Hordeum vulgare) I Andresen, W Becker, K Schlüter, J Burges, B Parthier, K Apel Plant molecular biology 19, 193-204, 1992 | 218 | 1992 |
| JIP60, a methyl jasmonate-induced ribosome-inactivating protein involved in plant stress reactions S Reinbothe, C Reinbothe, J Lehmann, W Becker, K Apel, B Parthier Proceedings of the National Academy of Sciences 91 (15), 7012-7016, 1994 | 211 | 1994 |
| The Down syndrome-related protein kinase DYRK1A phosphorylates p27Kip1 and Cyclin D1 and induces cell cycle exit and neuronal differentiation U Soppa, J Schumacher, V Florencio Ortiz, T Pasqualon, F Tejedor, ... Cell cycle 13 (13), 2084-2100, 2014 | 173 | 2014 |
| Molecular cloning of a protein serine/threonine phosphatase containing a putative regulatory tetratricopeptide repeat domain. W Becker, H Kentrup, S Klumpp, JE Schultz, HG Joost Journal of Biological Chemistry 269 (36), 22586-22592, 1994 | 171 | 1994 |
| Pleiotropy of leptin receptor signalling is defined by distinct roles of the intracellular tyrosines P Hekerman, J Zeidler, S Bamberg‐Lemper, H Knobelspies, D Lavens, ... FEBS Journal 272 (1), 109-119, 2005 | 161 | 2005 |
| Cloning of a novel family of mammalian GTP-binding proteins (RagA, RagBs, RagB1) with remote similarity to the Ras-related GTPases A Schürmann, A Brauers, S Maßmann, W Becker, HG Joost Journal of Biological Chemistry 270 (48), 28982-28988, 1995 | 150 | 1995 |
| Identification of the critical sequence elements in the cytoplasmic domain of leptin receptor isoforms required for Janus kinase/signal transducer and activator of … G Bahrenberg, I Behrmann, A Barthel, P Hekerman, PC Heinrich, ... Molecular Endocrinology 16 (4), 859-872, 2002 | 145 | 2002 |
| Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling B Hämmerle, E Ulin, J Guimera, W Becker, F Guillemot, FJ Tejedor Development 138 (12), 2543-2554, 2011 | 139 | 2011 |
| Characterization of Cyclin L2, a Novel Cyclin with an Arginine/Serine-rich Domain. PHOSPHORYLATION BY DYRK1A AND COLOCALIZATION WITH SPLICING FACTORS. K Graaf, P Hekerman, O Spelten, A Herrmann, LC Packman, K Bussow, ... Journal of Biological Chemistry 279 (6), 4612-4624, 2004 | 131 | 2004 |
| 10-Iodo-11 H-indolo [3, 2-c] quinoline-6-carboxylic Acids Are Selective Inhibitors of DYRK1A H Falke, A Chaikuad, A Becker, N Loaëc, O Lozach, S Abu Jhaisha, ... Journal of medicinal chemistry 58 (7), 3131-3143, 2015 | 126 | 2015 |
Heikki KainulainenFaculty of Sport and Health Sciences, Biology of Physical Activity, University of JyväskyläVerified email at jyu.fi
